Lood, relieve pain and kill worms.[15] Currently, the leaves are used for the remedy of wounds, aphtha, bedsores and malaria, too as diet-induced hypercholesterolemia,among other individuals.[16-18] Protective effects of extracts from C. cajan leaf against hypoxic-ischemic brain harm and alcohol-induced liver harm have also been reported.[19] Chemical constituent investigations have indicated that C. cajan leaves are rich in flavonoids and stilbenes, which are regarded responsible for the effective efficacies of C. cajan leaves on human wellness.[20-22] T. indica, local name tetul, can be a perennial herb belonging to the dicotyledonous loved ones of Fabaceae. It grows naturally in tropical and subtropical regions and now is amongst the most significant plant sources as meals supplies and is accepted as herbal medicine in parts in the world.[23] ItPharmacognosy Research | April-June 2014 | Vol 6 | Issuewas utilized as a regular medicine for the management of diabetes mellitus inhuman and experimental animals. [24,25] The prospective antioxidant activity of Tamarind seeds has currently been reported.[26,27] T. indica seed coat may play a vital role in chemical protection from oxidative harm by possessing endogenous antioxidants for example phenolic compounds. The prospective antioxidant activity of Tamarind seeds have already been reported as well as the isolated antioxidant elements are, 2-hydroxy-30, 40-dihydroxyacetophenone, methyl three, 4- ihydroxybenzoate, 3, 4-dihydroxyphenylacetate and epicatechin furthermore to oligomeric proanthocyanidins, phenolic compounds are procyanidin B2, epicatechin, procyanidin trimer, procyanidin tetramer, procyanidin pentamer, procyanidin hexamer, polymeric tannins, polymeric tannins.[28] It has been shown that aqueous extract of T. indica seeds have potent antidiabetic and antihyperlipidemic activities in STZ-induced diabetic male rat.[29] Right here we studied the methanolic extract of C. cajan root (MCC) and methanolic extract of T. indica seeds (MTI) to evaluate their hypoglycemic activity. As antidiabetic activity is closely associated with antioxidant activity, in this communication, we’ve got also assessed the antioxidant activity and total phenol content material of these two plants.Materials AND METHODSCollection of plant partsRoots in the plant C. cajan and seeds of T. indica , had been collected during the month of Could 2011 from the region of Konda Thana, Dhaka, Bangladesh. The plants were taxonomically identified and voucher specimen No- DACB 36424 and DACB 36425, have already been maintained for C. cajan and T. indica, respectively, inside the Bangladesh National Herbarium, Dhaka, Bangladesh.Price of 886593-45-9 Preparation of methanolic extract of C.1207625-15-7 Formula cajan rootAbout 387 g of dried powdered material was refluxed with 500 ml of 95 methanol for 3 h.PMID:23991096 The extracts have been then filtered by way of filter paper (Double Rings filter paper 102, 11.0 cm). The filtrates (methanol extract) were concentrated at 50 under minimize stress applying rotary evaporator (STUART RF3022C, UK) to afford an oily concentrate of greenish black color of extract. Finally, we got 16 g methanolic extract. The extract transferred to a closed container for further use and protection.Preparation of Methanolic extract of T. indica SeedsThe seeds of T. indica were dried in an oven for 2 days at 40 , crushed in an electrical grinder and then powdered. Extraction was performed by taking 25-g powder in 250 ml of distilled water for 18 h inside a soxhlet apparatus along with a deepNahar, et al.: Comparison of antidiabetic a.