JB, Kavishe RA, Rijpma SR, Russel FG: The ABCs of multidrug resistance in malaria. Trends Parasitol 2010, 26:440?46. 15. Warhurst DC: Polymorphism in the Plasmodium falciparum chloroquineresistance transporter protein hyperlinks verapamil enhancement of chloroquine sensitivity together with the clinical efficacy of amodiaquine. Malar J 2003, 2:31. 16. Wellems TE, Plowe CV: Chloroquine-resistant malaria. J Infect Dis 2001, 184:770?76. 17. Alifrangis M, Lusingu JP, Mmbando B, Dalgaard MB, Vestergaard LS, Ishengoma D, Khalil IF, Theander TG, Lemnge MM, Bygbjerg IC: Five-year surveillance of molecular markers of Plasmodium falciparum antimalarial drug resistance in Korogwe District, Tanzania: accumulation on the 581G mutation within the P. falciparum dihydropteroate synthase gene. Am J Trop Med Hyg 2009, 80:523?27. 18. Malmberg M, Ngasala B, Ferreira PE, Larsson E, Jovel I, Hjalmarsson A, Petzold M, Premji Z, Gil JP, Bjorkman A, Martensson A: Temporal trends of molecular markers linked to artemether-lumefantrine tolerance/ resistance in Bagamoyo district. Tanzania. Malar J 2013, 12:103.Mohammed et al. Malaria Journal 2013, 12:415 http://malariajournal/content/12/1/Page 7 of19. Polski JM, Kimzey S, Percival RW, Grosso LE: Fast and effective processing of blood specimens for diagnostic PCR working with filter paper and Chelex100. Mol Pathol 1998, 51:215?17. 20. Schneider AG, Premji Z, Felger I, Smith T, Abdulla S, Beck HP, Mshinda H: A point mutation in codon 76 of pfcrt of P. falciparum is positively selected for by chloroquine treatment in Tanzania. Infect Genet Evol 2002, 1:183?89. 21. Schonfeld M, Barreto MI, Schunk M, Maduhu I, Maboko L, Hoelscher M, Berens-Riha N, Kitua A, Loscher T: Molecular surveillance of drug-resistance associated mutations of Plasmodium falciparum in south-west Tanzania. Malar J 2007, six:2. 22. Khalil IF, Alifrangis M, Tarimo DS, Staalso T, Satti GM, Theander TG, Ronn AM, Bygbjerg IC: The roles from the pfcrt 76 T and pfmdr1 86Y mutations, immunity along with the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with various transmission intensities.Methyl 5-amino-2-bromo-4-methylbenzoate Chemscene Ann Trop Med Parasitol 2005, 99:441?48.Price of 131726-65-3 23.PMID:31085260 Temu EA, Kimani I, Tuno N, Kawada H, Minjas JN, Takagi M: Monitoring chloroquine resistance using Plasmodium falciparum parasites isolated from wild mosquitoes in Tanzania. Am J Trop Med Hyg 2006, 75:1182?187. 24. Sisowath C, Petersen I, Veiga MI, Martensson A, Premji Z, Bjorkman A, Fidock DA, Gil JP: In vivo collection of Plasmodium falciparum parasites carrying the chloroquine-susceptible pfcrt K76 allele following therapy with artemether-lumefantrine in Africa. J Infect Dis 2009, 199:750?57. 25. Lemnge M, Alifrangis M, Kafuye MY, Segeja MD, Gesase S, Minja D, Massaga JJ, Ronn AM, Bygbjerg IC: High reinfection rate and therapy failures in children treated with amodiaquine for falciparum malaria in Muheza villages, Northeastern Tanzania. Am J Trop Med Hyg 2006, 75:188?93. 26. Alifrangis M, Dalgaard MB, Lusingu JP, Vestergaard LS, Staalsoe T, Jensen AT, Enevold A, Ronn AM, Khalil IF, Warhurst DC, Lemnge MM, Theander TG, Bygbjerg IC: Occurrence of the Southeast Asian/South American SVMNT haplotype of your chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania. J Infect Dis 2006, 193:1738?741. 27. Kamugisha E, Bujila I, Lahdo M, Pello-Esso S, Minde M, Kongola G, Naiwumbwe H, Kiwuwa S, Kaddumukasa M, Kironde F, Swedberg G: Big differences in prevalence of Pfcrt and Pfmdr1 mutations betw.